Kevin McCairn is all over a Russian paper like a rash “Nice find TMN, I'll stream about this paper later today and what it means with respect to PRION exposure ..."
Bit of a long read and very much in the weeds going as far as the technology can penetrate. (No nanoparticles within nanoparticles yet!)
From here (h/t Ranger71):
And here:
I can’t access the live stream, maybe because I haven’t paid Twitter-X for the privileges?
Self-assembling nano-structures? Where have I heard that before? Oh yes:
“We all are part of an international collaborative team effort to shed light on the self-assembly nanotechnology in the C19 injectables. In this interview we present Dr. David Nixon’s time lapsed video footage showing that microchips assemble and disassemble and then reassemble again - possibly indefinitely continuing this process. This never before seen time lapsed footage from of microscopy images proves that this extremely advanced technology can easily be overlooked - but when carefully and patiently researched, can be documented. There is a virtual blueprint to this technology that controls intelligently this assembly and disassembly process.”
Okay, keep in mind I have no background or training in this highly specialised area, here are a couple more background links I have looked over:
From May 2023 – Not in a C19 context!
“Self-assembly of amyloid-β peptides leads to oligomers, protofibrils, and fibrils that are likely instigators of neurodegeneration in Alzheimer’s disease. We report results of time-resolved solid state nuclear magnetic resonance (ssNMR) and light scattering experiments on 40-residue amyloid-β (Aβ40) that provide structural information for oligomers that form on time scales from 0.7 ms to 1.0 h after initiation of self-assembly by a rapid pH drop.”
A few years earlier in March 2021:
“The currently developed vaccines against SARS-CoV-2 include the RBD in their immunogen. With a similar objective, a new study developed an RBD protein-based vaccine candidate against the SARS-CoV-2, using self-assembling Helicobacter pylori-bullfrog ferritin nanoparticles as an antigen delivery system. The study is published recently in the journal mBio (by the American Society of Microbiology).”
Jeremiah!!! The referenced study is here:
Also 2021, this time July:
”Nanoparticle (NP) antigens are highly immunogenic based on their unique physicochemical properties, making them molecular scaffolds to present soluble vaccine antigens. Here, viral targets (113-354 aas) were genetically fused to N terminal of mi3, a protein that self-assembles into nanoparticles composed of 60 subunits. With transmission electron microscopy, it was confirmed that target-mi3 fusion proteins which have insertions of up to 354 aas in N terminal form intact NPs. Moreover, viral targets are surface-displayed on NPs as indicated in dynamic light scattering.”
“Collectively, this structure-based, self-assembling NP provides an attractive platform to improve the potency of subunit vaccine for emerging pathogens.”
Maybe a few charcoal strokes on the blank canvass of my knowledge! Nano-particles self assemble and are useful?
Ok, on to the Russian paper here:
I won’t attempt to go into any detail, but I will just highlight a few pieces from the paper. I confess to wondering whether I am reading about the infection of the SARS-COV2 virus or the injection of the C19 mRNA vaccine! Pretty sure it’s the SARS-COV2 virus – maybe it just doesn’t matter any more if Dr Philip MacMillan’s analysis is anything to go by and it is all about reinfection risk, regardless of unvaxx/vaxx status and dosage!
I think it has more samples than just the nasal swab from one man taken in Moscow in March 2020!
“Self-assembling nanoparticles (saNP) and nanofibers were found in the recombinant coronavirus SARS-CoV-2 S1, S2, RBD and N proteins.”
Ah, so these nanoparticles are the same or slightly different from the mRNA nanoparticles?
“Amyloid-like structures were revealed in the SARS-CoV-2 S1, S2, RBD and N saNP by means of their interaction with Thioflavin T and Congo Red dyes.
Taken together, spontaneous formation of the amyloid-like self-assembling nanostructures due to the internal affinity of the SARS-CoV-2 virion proteins might induce proteinopathy in patients, including conformational neurodegenerative diseases, change stability of vaccines and diagnostic systems.”
All too familiar terms – well except maybe for “virion” and “amyloid” – the impacts are nasty. Ok one more snippet then some hope for the future:
“COVID-19 is caused by the enveloped spherical β-coronavirus SARS-CoV-2 with a longest positive single-stranded RNA genome of up to 31 kb in length.
The virions consist of structural proteins such as the spike (S), membrane (M), envelope (E), and nucleocapsid (N) proteins.
Additionally, there is the hemagglutinin-esterase (HE) protein in some β-coronaviruses [23,24]. The S, M, and E proteins are embedded in the envelope and the N protein interacts with the viral RNA, forming the nucleocapsid [23].
S protein is necessary for β-coronaviruses to attach to the host cell and enter. The host protease furin cleaves the full-length precursor S glycoprotein into two associated polypeptides: S1 and S2 [25].”
Again, similar but differences between the SARS-COV2 virus and the C19 mRNA injection contents?
Right, ok, here’s the “hope” part. Apparently there are 300 “vaccines” in development. Let’s hope their clinical trials are honest and any manufacturing scale-up has 100% integrity!
This is the hopeful snippet:
“An ultrathin nanosheets were fabricated from copper indium thiophosphate (CuInP2S 6, denoted CIPS) for anti-SARS-CoV-2 therapy, as a decontamination agent and surface-coating material to reduce SARS-CoV-2 infectivity.
CIPS exhibits high and selective binding capacity (dissociation constant (KD) < 1 pM) for the SARS-CoV-2 spike protein RBD domain, inhibiting virus entry and infection in angiotensin converting enzyme 2 (ACE2)-bearing cells, human airway epithelial organoids and human ACE2-transgenic mice.
On association with CIPS, the virus is quickly phagocytosed and eliminated by macrophages, suggesting that CIPS could be successfully used to capture and facilitate virus elimination by the host [29].”
Sort of a Russian version of IVM?
Kevin will focus on what is probably far more important, but I thought I would share what looked interesting to myself, as a lay person!
Here is the “Conclusion”
“Taken together, one can conclude that saNP from the SARS-CoV-2 recombinant proteins S1, S2, and N isolated from the transformed bacterial E.coli cells and RBD glycoprotein fragment produced in the transfected eukaryotic Expi293F cells can affect both immunodiagnostics because of shielding of coroviral structural antigens inside solid NP and vaccinology with recombinant subunit vaccines with possible induction of Th1 immune response due to unspecific endocytosis of saNP and probable …”
So there you have it! The Russia paper cuts off most of its end sections with the “…” syntax. Maybe there are more secrets hidden to maintain an intellectual 3D chess sort of thing!
Onwards!
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Peter, This is NOT Keven McKernan (who is a friend). This is Kevin McCairn whom I do not know. Still looks more-than-interesting but better to get it right.
You’ve muddled up your Kevins! It’s Kevin McCairn who tweeted and is a neuroscientist with a particular interest in prions and amyloids from the virus/injections.