You don’t need it for integration. When the nucleus dissolves during mitosis, it’s wide open for all kinds of possible integration events. That is why delivering all of these DNA fragments directly into the cytoplasm is a dangerous proposition and why Moderna has dozens of patents that discuss this as a major issue.
Wow, BraveAI needs some training! This is a problematic answer from it.
Grok gives a much more accurate answer:
See new posts
Is this statement correct? “ "In fact, SV40 is a monkey virus, and its genome is composed of monkey DNA. ”
The statement "In fact, SV40 is a monkey virus, and its genome is composed of monkey DNA" is partially correct but requires clarification. SV40, or Simian Virus 40, is indeed a virus originally identified in monkeys, specifically in rhesus macaque and African green monkey kidney cells. However, the assertion that its "genome is composed of monkey DNA" is not entirely accurate in the context of how viral genomes are typically understood:
Viral Genome Composition: The genome of SV40 is a double-stranded circular DNA molecule, which is characteristic of polyomaviruses. It does not contain "monkey DNA" in the sense of being derived from the host's cellular DNA; rather, it is the genetic material of the virus itself, which has evolved alongside its hosts but is distinct from them. The genome consists of viral genes necessary for replication, transcription, and the production of viral proteins.
Source of the Term: The term "monkey DNA" in this context might be misleading because it suggests that the viral DNA is directly from the monkey's genetic material, which is not the case. Instead, SV40 has its own unique genetic sequence that is adapted to infect monkey cells, among other species including humans.
Integration and Host DNA: While SV40 can integrate into host DNA in certain conditions, particularly in transformed or non-permissive cells, this integration does not mean the viral genome becomes "monkey DNA". It remains viral DNA, albeit integrated into the host genome.
Therefore, a more accurate statement would be: "SV40 is a monkey virus, and its genome is a unique sequence of DNA that is adapted to infect monkey cells."
This clarification reflects the biological reality that SV40's DNA is inherently viral, not directly derived from the host's genome, although it can interact with host DNA in specific cellular contexts.
Furthermore:
SV40 Promoters in Gene Therapy:
Use in Gene Therapy: SV40 promoters are indeed used in some gene therapy vectors due to their strong transcriptional activity. They can drive high levels of gene expression, which is desirable for ensuring therapeutic genes are sufficiently expressed in target cells. However, the primary function of these promoters in gene therapy contexts is to enhance transcription, not necessarily to facilitate integration into the host genome. The integration of genetic material into the host cell's DNA is more commonly associated with the vector's integration mechanism rather than the promoter itself. For instance, vectors like retroviruses and lentiviruses have natural mechanisms for integration, whereas SV40 vectors might rely on other means for DNA delivery, such as plasmid DNA or viral particles without integration capabilities.
Integration Concerns: While SV40 promoters themselves do not directly cause integration, there are concerns about the potential risks associated with the integration of any foreign DNA into the human genome, particularly when using viral vectors that might inadvertently integrate:
Oncogenic Potential: SV40 has a known oncogenic potential in animal models, primarily through its large T antigen, which can interfere with tumor suppression pathways by binding to p53 and pRb proteins. The concern in gene therapy is not just the promoter but the entire vector, including any oncogenic sequences or elements that could lead to uncontrolled cell growth if inserted near or into oncogenes or tumor suppressor genes.
Regulatory and Manufacturer Concerns: Both regulatory bodies like the FDA and manufacturers of gene therapies are aware of these risks. There's stringent oversight regarding the use of SV40 elements in gene therapy vectors, focusing on minimizing the risk of oncogene activation or tumor suppressor gene inactivation. Here are some specific concerns:
Insertional Mutagenesis: This is the risk of a therapeutic vector inserting near or within genes that regulate cell growth, potentially leading to oncogenesis. Regulatory bodies require extensive preclinical and clinical testing to assess this risk.
DNA Contamination: There have been discussions and concerns about DNA contaminants, including SV40 sequences, in gene therapy products, especially if these sequences might lead to unintended genomic integration or expression issues.
Regulatory Measures: To mitigate these risks, regulatory bodies enforce guidelines for vector design, manufacturing processes to limit DNA contamination or integration events, and thorough characterization of the vector's behavior in cells, including integration patterns and potential oncogenic effects.
In conclusion, while SV40 promoters are used for their transcriptional efficiency in gene therapy, the actual integration into the genome is more a concern of the vector's delivery mechanism. However, the presence of SV40 elements in these vectors does raise specific concerns about oncogenic risk, leading to cautious use, rigorous testing, and regulatory oversight to minimize potential adverse effects.
Thanks for this. I have heard of Grok and might give it a go. - statements like "SV40 vectors might rely on other means for DNA delivery, such as plasmid DNA or viral particles without integration capabilities. " are not conclusive!
Also, the amounts of DNA injected and the fact that SV40 was not declared to regulators anywhere also does not fill me with confidence!
The most horrific part of your title is “Monkey DNA”.
There never was monkey DNA even in the contaminated polio vaccines. It was whole virus contamination of a type known to infect monkeys used in lab experiments.
The title should be something along the lines of “bacterial plasmid DNA with SV40 promoters”.
This is why you get horribly misinformed commentary on your article like this:
“It is also possible or likely that the initiators of C19 vaccine knew that monkey DNA would be found and this in an increment of numbers; then it being 'normalized', and then it is proven that all people are subhuman apart from an Z-elite, and sub- or con-sequently they are our rulers.”
He doesn’t have a clue as to what he’s talking about. It’s both embarrassing and frustrating.
"In fact, SV40 is a monkey virus, and its genome is composed of monkey DNA. According to the search results, SV40 DNA is a double-stranded circular DNA molecule with 5243 base pairs, which is characteristic of a monkey polyomavirus."
As I understand it, the are of contention is whether the fragments are or are not infectious:
Again, from Brave AI:
"The (Pfizer) vaccine contains non-infectious, residual DNA fragments from the manufacturing process, specifically a portion of the SV40 promoter/enhancer sequence, which is present in a non-functional part of the plasmid used to make the vaccine. These fragments are not capable of causing cancer or any other health problems."
That non-infectious claim has not been demonstrated - in fact the manufacturing process has been severely challenged as a long way from perfect.
Is it your position that that fragments of SV40 DNA do not have significant impacts onn human DNA = [pst injection of Pfizer shots?
Why would you ever use “monkey DNA” in your title????
It’s misnomers like this that harm the scientific truth initiative.
The subject is an engineered plasmid containing a 72 bp snippet of the SV40 virus to drive translation of mRNA in the E. coli based manufacturing process.
The SV40 VIRAL GENOME is 5,523 bp long. Hence the term “snippet”, is appropriate for the portion of it used as a promotor in these plasmids.
This should NOT be confused with the SV40 virus, known to infect monkeys and was the cause of VIRAL contamination of early vaccines which were grown using vero kidney cells from monkeys.
Next, you’ve conflated an engineered plasmid with the DNA of Family: Cercopithecidae and the Genuses of the African Green Monkey - Chlorocebus and Rhesus Macaque - Macaca, from which those vero cell lines were harvested, but whose DNA have absolutely no relationship to this plasmid or anything else being discussed.
We have to all be very careful with the terminology we use when describing things, because terms have specific meanings and you’ve managed to mangle two things to the point that anyone without any knowlege of the subject, upon reading the title of you post, would leave completely and utterly misinformed.
Your title is nearly the same as one put out by Dr Joseph Mercola, shortly after the discovery of this DNA contamination, which caused the researcher endless headaches for nearly 18 months having to correct the record as that story of “MONKEY DNA” and the conflation of a promotor with a plasmid kept confusing and misdirecting people. What a nightmare!!!
Be careful of what you write. Use the correct terminology instead of sensational words which are completely misleading and inappropriate. You can end up doing more harm than good if you don’t.
Do you have a substack I can cross post to correct the record that SV does not refer to a Simian/Moneky virus? I do try to refer to "fragments" f the virus, rather than "whole" Simian/Monkey SV40 virus - but it sounds like the world would benefit from your more detailed knowledge, qualifications and expertise. I relay what I understand from what I read, so maybe you can better inform the people of the world who may well be labouring under the same misunderstandings as non-medics/scientists such as myself. Or maybe I should just post your comment as an article if you do not have a substwack?.
You can take solice on this christmas eve with the knowledge, that, considering 99% of the worlds gutless wonders are decking the halls and mistletoe kissing, ... and considering there are millions of f#ckers out here just like me, that given the chance, would end these criminals in an instant, please enjoy some festivities, and share as much love and joy as you can exude, because this experience is limited severely! We, the good, will be rewarded with KARMA!
This unraveling story of harms caused by the Covid injection continues like a weird and very bad scifi movie. I worried that extraneous DNA would infiltrate and mix with the natural human DNA from the minute they announced that they would use mRNA "vaccinations." This is just unbelievable.
It is also possible or likely that the initiators of C19 vaccine knew that monkey DNA would be found and this in an increment of numbers; then it being 'normalized', and then it is proven that all people are subhuman apart from an Z-elite, and sub- or con-sequently they are our rulers.
You don’t need it for integration. When the nucleus dissolves during mitosis, it’s wide open for all kinds of possible integration events. That is why delivering all of these DNA fragments directly into the cytoplasm is a dangerous proposition and why Moderna has dozens of patents that discuss this as a major issue.
Wow, BraveAI needs some training! This is a problematic answer from it.
Grok gives a much more accurate answer:
See new posts
Is this statement correct? “ "In fact, SV40 is a monkey virus, and its genome is composed of monkey DNA. ”
The statement "In fact, SV40 is a monkey virus, and its genome is composed of monkey DNA" is partially correct but requires clarification. SV40, or Simian Virus 40, is indeed a virus originally identified in monkeys, specifically in rhesus macaque and African green monkey kidney cells. However, the assertion that its "genome is composed of monkey DNA" is not entirely accurate in the context of how viral genomes are typically understood:
Viral Genome Composition: The genome of SV40 is a double-stranded circular DNA molecule, which is characteristic of polyomaviruses. It does not contain "monkey DNA" in the sense of being derived from the host's cellular DNA; rather, it is the genetic material of the virus itself, which has evolved alongside its hosts but is distinct from them. The genome consists of viral genes necessary for replication, transcription, and the production of viral proteins.
Source of the Term: The term "monkey DNA" in this context might be misleading because it suggests that the viral DNA is directly from the monkey's genetic material, which is not the case. Instead, SV40 has its own unique genetic sequence that is adapted to infect monkey cells, among other species including humans.
Integration and Host DNA: While SV40 can integrate into host DNA in certain conditions, particularly in transformed or non-permissive cells, this integration does not mean the viral genome becomes "monkey DNA". It remains viral DNA, albeit integrated into the host genome.
Therefore, a more accurate statement would be: "SV40 is a monkey virus, and its genome is a unique sequence of DNA that is adapted to infect monkey cells."
This clarification reflects the biological reality that SV40's DNA is inherently viral, not directly derived from the host's genome, although it can interact with host DNA in specific cellular contexts.
Furthermore:
SV40 Promoters in Gene Therapy:
Use in Gene Therapy: SV40 promoters are indeed used in some gene therapy vectors due to their strong transcriptional activity. They can drive high levels of gene expression, which is desirable for ensuring therapeutic genes are sufficiently expressed in target cells. However, the primary function of these promoters in gene therapy contexts is to enhance transcription, not necessarily to facilitate integration into the host genome. The integration of genetic material into the host cell's DNA is more commonly associated with the vector's integration mechanism rather than the promoter itself. For instance, vectors like retroviruses and lentiviruses have natural mechanisms for integration, whereas SV40 vectors might rely on other means for DNA delivery, such as plasmid DNA or viral particles without integration capabilities.
Integration Concerns: While SV40 promoters themselves do not directly cause integration, there are concerns about the potential risks associated with the integration of any foreign DNA into the human genome, particularly when using viral vectors that might inadvertently integrate:
Oncogenic Potential: SV40 has a known oncogenic potential in animal models, primarily through its large T antigen, which can interfere with tumor suppression pathways by binding to p53 and pRb proteins. The concern in gene therapy is not just the promoter but the entire vector, including any oncogenic sequences or elements that could lead to uncontrolled cell growth if inserted near or into oncogenes or tumor suppressor genes.
Regulatory and Manufacturer Concerns: Both regulatory bodies like the FDA and manufacturers of gene therapies are aware of these risks. There's stringent oversight regarding the use of SV40 elements in gene therapy vectors, focusing on minimizing the risk of oncogene activation or tumor suppressor gene inactivation. Here are some specific concerns:
Insertional Mutagenesis: This is the risk of a therapeutic vector inserting near or within genes that regulate cell growth, potentially leading to oncogenesis. Regulatory bodies require extensive preclinical and clinical testing to assess this risk.
DNA Contamination: There have been discussions and concerns about DNA contaminants, including SV40 sequences, in gene therapy products, especially if these sequences might lead to unintended genomic integration or expression issues.
Regulatory Measures: To mitigate these risks, regulatory bodies enforce guidelines for vector design, manufacturing processes to limit DNA contamination or integration events, and thorough characterization of the vector's behavior in cells, including integration patterns and potential oncogenic effects.
In conclusion, while SV40 promoters are used for their transcriptional efficiency in gene therapy, the actual integration into the genome is more a concern of the vector's delivery mechanism. However, the presence of SV40 elements in these vectors does raise specific concerns about oncogenic risk, leading to cautious use, rigorous testing, and regulatory oversight to minimize potential adverse effects.
Thanks for this. I have heard of Grok and might give it a go. - statements like "SV40 vectors might rely on other means for DNA delivery, such as plasmid DNA or viral particles without integration capabilities. " are not conclusive!
Also, the amounts of DNA injected and the fact that SV40 was not declared to regulators anywhere also does not fill me with confidence!
The most horrific part of your title is “Monkey DNA”.
There never was monkey DNA even in the contaminated polio vaccines. It was whole virus contamination of a type known to infect monkeys used in lab experiments.
The title should be something along the lines of “bacterial plasmid DNA with SV40 promoters”.
This is why you get horribly misinformed commentary on your article like this:
“It is also possible or likely that the initiators of C19 vaccine knew that monkey DNA would be found and this in an increment of numbers; then it being 'normalized', and then it is proven that all people are subhuman apart from an Z-elite, and sub- or con-sequently they are our rulers.”
He doesn’t have a clue as to what he’s talking about. It’s both embarrassing and frustrating.
I am willing to b corrected where I am wrong.
From Brave AI:
"In fact, SV40 is a monkey virus, and its genome is composed of monkey DNA. According to the search results, SV40 DNA is a double-stranded circular DNA molecule with 5243 base pairs, which is characteristic of a monkey polyomavirus."
As I understand it, the are of contention is whether the fragments are or are not infectious:
Again, from Brave AI:
"The (Pfizer) vaccine contains non-infectious, residual DNA fragments from the manufacturing process, specifically a portion of the SV40 promoter/enhancer sequence, which is present in a non-functional part of the plasmid used to make the vaccine. These fragments are not capable of causing cancer or any other health problems."
That non-infectious claim has not been demonstrated - in fact the manufacturing process has been severely challenged as a long way from perfect.
Is it your position that that fragments of SV40 DNA do not have significant impacts onn human DNA = [pst injection of Pfizer shots?
Why would you ever use “monkey DNA” in your title????
It’s misnomers like this that harm the scientific truth initiative.
The subject is an engineered plasmid containing a 72 bp snippet of the SV40 virus to drive translation of mRNA in the E. coli based manufacturing process.
The SV40 VIRAL GENOME is 5,523 bp long. Hence the term “snippet”, is appropriate for the portion of it used as a promotor in these plasmids.
This should NOT be confused with the SV40 virus, known to infect monkeys and was the cause of VIRAL contamination of early vaccines which were grown using vero kidney cells from monkeys.
Next, you’ve conflated an engineered plasmid with the DNA of Family: Cercopithecidae and the Genuses of the African Green Monkey - Chlorocebus and Rhesus Macaque - Macaca, from which those vero cell lines were harvested, but whose DNA have absolutely no relationship to this plasmid or anything else being discussed.
We have to all be very careful with the terminology we use when describing things, because terms have specific meanings and you’ve managed to mangle two things to the point that anyone without any knowlege of the subject, upon reading the title of you post, would leave completely and utterly misinformed.
Your title is nearly the same as one put out by Dr Joseph Mercola, shortly after the discovery of this DNA contamination, which caused the researcher endless headaches for nearly 18 months having to correct the record as that story of “MONKEY DNA” and the conflation of a promotor with a plasmid kept confusing and misdirecting people. What a nightmare!!!
Be careful of what you write. Use the correct terminology instead of sensational words which are completely misleading and inappropriate. You can end up doing more harm than good if you don’t.
Do you have a substack I can cross post to correct the record that SV does not refer to a Simian/Moneky virus? I do try to refer to "fragments" f the virus, rather than "whole" Simian/Monkey SV40 virus - but it sounds like the world would benefit from your more detailed knowledge, qualifications and expertise. I relay what I understand from what I read, so maybe you can better inform the people of the world who may well be labouring under the same misunderstandings as non-medics/scientists such as myself. Or maybe I should just post your comment as an article if you do not have a substwack?.
and guess what? Nothing will happen to the murderers and their enablers and cheerleaders.
You can take solice on this christmas eve with the knowledge, that, considering 99% of the worlds gutless wonders are decking the halls and mistletoe kissing, ... and considering there are millions of f#ckers out here just like me, that given the chance, would end these criminals in an instant, please enjoy some festivities, and share as much love and joy as you can exude, because this experience is limited severely! We, the good, will be rewarded with KARMA!
Bless you alll
...
This unraveling story of harms caused by the Covid injection continues like a weird and very bad scifi movie. I worried that extraneous DNA would infiltrate and mix with the natural human DNA from the minute they announced that they would use mRNA "vaccinations." This is just unbelievable.
W.T.F. !!!
What could possibly go wrong
It is also possible or likely that the initiators of C19 vaccine knew that monkey DNA would be found and this in an increment of numbers; then it being 'normalized', and then it is proven that all people are subhuman apart from an Z-elite, and sub- or con-sequently they are our rulers.
It’s not Monkey DNA, it is an engineered plasmid DNA.
https://peterhalligan.substack.com/p/75-australians-found-with-monkey/comment/83169291?r=qx4qj&utm_medium=ios
The answer is the same as it was 4 years ago, wake people up. Undermine the Traitor's power foundation, compliance
MERRY CHRISTMAS!
Merry Christmas Pete, you take care mate.
Scoop by scoop we're slowly moving the mountain